Faculty
  

Steven G. Self, Ph.D.,
Executive Director

Dr. Self serves as Executive Director of SCHARP and has been actively involved in HIV/AIDS research since the mid 1990s. He has played an integral role in the scientific leadership and development of the HVTN since its inception.

Dr. Self also holds the following positions:
  • Full Member in the Program in Biostatistics and Biomathematics at the Fred Hutchinson Cancer Research Center (he has served as head of that program since 1994)

  • Professor of Biostatistics at the University of Washington School of Public Health

  • Affiliate Professor of Biostatistics at the Bloomberg School of Public Health of the Johns Hopkins University

Dr. Self's research interests focus on the design, conduct, and analysis of HIV prevention trials, with a particular emphasis on HIV vaccines and on the development of novel statistical methods. In this area, he has published on a wide variety of topics, including statistical designs and definition of endpoints for vaccine efficacy trials, analytic methods for the elucidation of immunologic and virologic correlates of protection, methods for the analysis of HIV genetic variation, the optimal design of reagents for assays of cellular immune response, stochastic mathematical models for describing the dynamics of early HIV infection, methods for the analysis of differential expression and coexpression of genes, and methods for the analysis of comparative genome hybridization data.

Dr. Self currently serves on a variety of scientific advisory boards and review panels, including the following:
  • Board of Scientific Counselors for the U.S. National Cancer Institute

  • Scientific Advisory Board for the Terry Beirn Community Programs for Clinical Research on AIDS

  • U.S. FDA Vaccine and Related Biological Products Advisory Committee

  • Scientific Advisory Board for the HIV Vaccine Development Program at St. Jude Children's Hospital

  • Dr. Self also serves as Chair of the Data and Safety Monitoring Board for the National Cancer Institute HPV Vaccine Efficacy Trial, member of data and safety monitoring boards for a variety of other clinical trials in the areas of cancer therapeutics and infectious disease treatment and prevention.